New supplement designed to combat ‘Ozempic face’, other side effects

Losing face? Take heart. There’s a new supplement on the market that promises to put an end to the hangover “Ozempic face” aesthetic — in addition to some of the drug’s other unpleasant side effects.

Ozempic is part of a class of diabetes and obesity drugs that mimic the hormone GLP-1 that the body naturally produces after eating, suppressing appetite and stimulating weight loss.

But for some, rapid weight loss can create skin elasticity problems that manifest in sunken eyes, sagging cheeks and sagging skin, often making the user look older and more deflated.

Extreme weight loss in a short period of time – with or without GLP-1 – can cause loss of skin elasticity due to breakdown of the skin barrier and rapid depletion of essential fatty acids. The phenomenon has recently been dubbed “Ozempic Face”, with stars such as Sharon Osbourne – who admitted to weighing under 100lbs earlier this year – accused of having it.

Upper East Side plastic surgeon Dr. Robert Schwarcz previously told The Post that losing fat in the central area of ​​the cheeks and neck can result in “significant aging.” With long-term use, the temples can also be affected, giving a “skeletal eye look that makes people look older than they should be,” he said.

In response to this skeletal deflation, Replenza has launched a line of dietary supplements designed for people taking GLP-1 medications.

Replenza Daily Supplement contains a blend of probiotics and enzymes for gut health, a patented ingredient to aid in nutrient absorption. a complex of B vitamins and ashwagandha, which has been shown to reduce stress symptoms, increase energy, and improve mood, sleep, and focus. A one-month supply costs $24.98.

Meanwhile, Replenza Daily Replenisher, retailing for $49.98 for a month’s supply, is a powdered supplement that supports skin elasticity and digestive function.

“Digestive health and muscle recovery are vital areas that are often overlooked on a weight loss journey using GLP-1 medications,” said Dr. Rajesh Dhirmalani, a board-certified gastroenterologist and member of Replenza’s advisory board.

“Replenza is designed to support nutrition from the inside and is made with amino acids, prebiotics, probiotics and essential nutrients.”

Speaking to The Post, Dietitian and Replenza Advisory Board Member Danielle Schupp emphasized the importance of nutrition and nutritional support for those taking GLP-1 medications.

“As a nutritionist with 30 years of expertise in weight management, GLP-1 is a life-changing drug for many people, and when combined with the right nutrition program, the results are astounding,” she said. “That’s why I often recommend supplements to fill the nutritional gaps created for those taking GLP medications.”

Ozempic user Quenby Erickson, who lost 45 pounds in seven months on the drug, previously told The Post that her progress on the Ozempic facial was gradual.

“It’s really hard to say for sure when I noticed my face was changing,” she said. “You just think it’s weight loss, and then you start looking in the mirror like, ‘Wait a minute, my skin is saggy now and it wasn’t before. I’ve aged a lot in a few months.’

Plastic surgeons say The ozemic face is less pronounced in women, because they are more likely to hide the fluctuations with fillers and makeup. In terms of fillers, surgeons have noticed an increase in demand for cosmetic fillers to combat Ozempic facial disease.

Along with causing people to lose face, the treatment has also been blamed for sagging glutes, called “Ozempic Butts,” vision problems, intestinal obstruction, foul scratches, gastrointestinal upset, stomach paralysis, and even changes in personality.

Replenza supplements are hitting the market just as the makers of Ozempic have developed a pill that can cause weight loss of up to 13% in three months, suggesting that weight loss and sagging face will continue to be a problem that needs to be addressed.